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3.8.1 Organisations and researchers should make sure that research involving animals adheres to all legal and ethical requirements and other applicable guidelines. They should consider the opportunities for reduction, replacement and refinement of involving animals in research projects and should refer to the relevant guidance.
3.8.2 When conducting, or collaborating in, research in other countries, organisations and researchers based in the UK should comply with the legal and ethical requirements existing in the UK and in the countries where the research is conducted. Similarly, organisations and researchers based abroad who participate in UKhosted research projects should comply with the legal and ethical requirements existing in the UK as well as those of their own country.
3.8.3 Organisations should set up systems to ensure the ethical, regulatory and peer review of research projects involving animals. The systems should include mechanisms to make sure that such research projects have been approved by all applicable bodies, ethical, regulatory or otherwise.
3.8.4 Organisations should make sure that their researchers are aware of the above systems and have access to all relevant guidance and legal and ethical frameworks.
3.8.5 Researchers should submit research projects involving animals for review by all relevant ethics committees and abide by the outcome of that review. They should also ensure that such research projects have been approved by all applicable bodies, ethical, regulatory or otherwise.
3.8.6 If researchers consider that animals involved in research are subject to unreasonable risk or harm, they must report their concerns to their manager or other appropriate person as identified by their organisation, and, where required, to the appropriate regulatory authority.